多不饱与脂肪酸对大鼠肠道菌群及其脂肪代谢相关基因的影响.pdf

多不饱与脂肪酸对大鼠肠道菌群及其脂肪代谢相关基因的影响.pdf

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f脚删删舢删舢册||J|『舢肼 Y2589138 TodeterminetheeffectofPUFAdieton factorsin microbiotaand cell Objective gut obesity-related MethodsAtotalof5weeksold30 femaleratswere dividedintothree healthy randomly groups: control diet andn-3 diet andfree and group,n-6 PUFA-containinggroup PUFA-containinggroup feeding waterfor weeks.Blood andfood wererecorded intake eight serum,bodyweight.1ength perdayduring thetrail fat ofnumberof of period.Body bacteria,thickness weight,epididymalpadweight,changes Mucus relative of cellfactorswereassessed.Thelevelsof Layer,andexpressionobesity-related Bifidobacterium(Bif),Lactobacillus(Lac),Akkermansia muciniphila(hkk),Clostridriumdifficile(Clo), cellfactors and Staphylococcusaureus(sta),Ecoli(Eco)andobesity-related wereassessed methodandthe levelofnesfatin-1wasassessedwestern ghrelin byqRT-PCR protein by The and Results fat ofn·3PUFA werelowerthancontrol bodyweightepididymalpadweight group inn-6 foodintakeWasalsolowerinn-3and inn一6 with group,andhigher group.The higher compared control of than thicknessn-3 Was control group.M

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