尖锐湿疣论文co2激光论文白介素2论文.docVIP

尖锐湿疣论文co2激光论文白介素2论文尖锐湿疣论文co2激光论文白介素2论文 CO2激光联合白介素2治疗尖锐湿疣临床疗效观察 【摘 要】 目的:评价co2激光联合白介素2治疗尖锐湿疣的临床疗效。方法:将入选患者随机分为两组，试验组患者激光治疗后，即给予60万iu白介素2加入0.9%氯化钠注射液500ml中静脉滴注，1天1次，1周用药5天，共3周。对照组患者激光治疗后，不再进行其他特殊处理。对所有治疗的患者连续随访6个月，观察创面愈合和皮损复发情况。 结果:试验组有5例复发，复发率为11.11%，对照组有19例复发，复发率为42.22%，两组复发率差异比较有统计学意义（χ2=12.57，p＜0.01）。结论::co2激光联合白介素2治疗尖锐湿疣，明显降低了尖锐湿疣的复发率，缩短了患者的治疗时间，减轻了患者的痛苦，缓解了他们的心理压力。 【关键词】 尖锐湿疣; co2激光; 白介素2 co2 laser combined with interleukin-2 in treatment of condyloma acuminate gong xianjun, fan yanhong, wang hongmei 1 department of dermatology, central hospital of shandong zaozhuang mining group, shandong 277011, china 2 central hospital of shandong zaozhuang mining group, shandong 277011, china 3 taozhuang town health clinic, shandong 277011, china 【abstract】 objectives: to evaluate the therapeutic effects of co2 laser combined with interleukin-2(il2) in the treatment of condyloma acuminate(ca). methods: the patients were randomly divided into two groups. the treatment group was treated with laser combined with venous injection of60mg il2 dissolved in 0.9% sodium chloride, once daily for three weeks, five days a week. the control group was only treated with laser. all the patients were followed for six months to observe the therapeutic effects and recurrence rates. results: the treatment group revealed 5 recurrence cases, the rate being 11.11%; the control group indicated 19 recurrence cases with the rate of 42.22%. the recurrence rates of the control were significantly higher than the treatment group(χ２＝１２.５７，ｐ＜０.０１）. conclusion: co2 laser treatment combined with il2 can significantly lower the recurrence rate of ca, shorten the therapeutic periods, reduce patients’ pain and relieve their psychological pressure. 【key words】 condyloma acuminate; co2 laser; interleukin-2 尖锐湿疣是临床上最常见的性传播疾病之一，是由人类乳头瘤病毒引起的增生性疾病。以往常用的治疗方法，如局部用药、激光、冷冻都能在一定程度上消除疣体，但复发率较高。我科采用co2激光联合白介素2治疗尖锐湿疣患者，明显降低了尖锐湿疣的复发率，疗效满意。现将结果报告如下。 1资料和方法 1.1一般资料所选的90例患者为2009年6月~2010年6月来我科就诊者。临床和（或）组织病理确诊为尖锐湿疣，且醋酸白试验阳性。90