ApplicationofAmino-FunctionalizedSBA-15TypeMesoporousSilicainOne-PotSynthesisofSpirooxindoles.pdfVIP

2012 Chinese Journal of Catalysis Vol. 33 No. 11 Article ID: 0253-9837(2012)11-1832-08 DOI: 10.1016/S1872-2067(11)60456-7 Article: 1832–1839 Application of Amino-Functionalized SBA-15 Type Mesoporous Silica in One-Pot Synthesis of Spirooxindoles 1,* 2 1 2 Ghodsi MOHAMMADI ZIARANI , Alireza BADIEI , Somayeh MOUSAVI , Negar LASHGARI , Afsaneh SHAHBAZI2 1 Department of Chemistry, Alzahra University, Vanak Square, P.O. Box 1993893973, Tehran, Iran 2School of Chemistry, College of Science, University of Tehran, Tehran, Iran Abstract: Amino-functionalized SBA-15 (SBA-Pr-NH ) has been used as a new basic nanocatalyst in the one-pot synthesis of spirooxindole 2 derivatives via the three-component condensation reaction of isatins, activated methylene reagents, and dimedone in an aqueous medium. SBA-Pr-NH2 has been established as an efficient heterogeneous nanoporous solid basic catalyst (pore size of 6 nm) that can be easily handled and removed from the reaction mixture by simple filtration, and also recovered and reused without noticeable loss of reactivity. Key words: amino-functionalized SBA-15; spirooxindoles; isatin; nano-reactor; green synthesis CLC number: O643 Document code: A Received 15 August 2012. Accepted 11 September 2012. *Corresponding author. Tel/Fax: +98-2188041344; E-mail:gmziarani@; gmohammadi@alzahra.ac.ir This work was supported by