王华东脓毒症的病理生理学从基础到临床解析.pdfVIP

脓毒症的病理生理学: 从基础到临床 王华东 （暨南大学医学院病理生理学系） 广东省自然科学基金重点项目 国家自然科学基金资助项目 一、脓毒症相关概念的新认识 • Roger Bone and colleagues (1991) :sepsis as a systemic inflammatory response syndrome (SIRS) that can occur during infection (American College of Chest Physicians/Society of Critical Care Medicine). Systemic inflammatory response syndrome (SIRS) criteria (≥2 must be present) • Body temperature38 ℃or 36 ℃; • Heart rate 90 beats per minute; • Respiratory rat