盐酸氨溴索与头孢他啶联用对新生儿感染性肺炎的疗效和安全性评价.docVIP

盐酸氨溴索与头孢他啶联用对新生儿感染性肺炎的疗效和安全性评价 　　【摘要】 目的：探讨盐酸氨溴索与头孢他啶协同治疗新生儿感染性肺炎的疗效和安全性评价。方法：选取本院儿科2013年1月-2014年2月收治的新生儿感染性肺炎患儿88例作为研究对象，随机将其分为观察组48例和对照组40例。对照组给予头孢他啶静脉滴注、常规吸氧、酸碱失衡纠正及支持治疗，观察组在对照组治疗的基础上给予盐酸氨溴索静脉滴注治疗，观察并比较两组患儿的治疗总有效率、肺炎症状、体征改善情况和不良反应发生情况。结果：观察组的治疗总有效率93.75%明显高于对照组的67.50%，差异有统计学意义（ 字2=10.1063，P=0.0015）。观察组患儿的咳喘消失时间、退热时间、肺部??音消除时间、平均住院时间均明显短于对照组，每日吸痰次数明显少于对照组，差异均有统计学意义（P中国论文网 /6/view-7254310.htm 　　【关键词】 盐酸氨溴索； 新生儿感染性肺炎； 疗效； 不良反应 　　The Safety Evaluation and Curative Effect of Ambroxol Hydrochloride Combined with Ceftazidime for the Treatment of Neonatal Infectious Pneumonia/XIONG Ying-chun.//Medical Innovation of China，2016，13（09）：062-064 　　【Abstract】 Objective：To investigate the effect and safety evaluation of Ambroxol Hydrochloride combined with Ceftazidime for the treatment of neonatal infectious pneumonia.Method：Eighty-eight cases of neonatal infectious pneumonia in our hospital from January 2013 to February 2014 were selected as the research objects，they were randomly divided into the observation group for 48 cases and the control group for 40 cases.The control group was given Ceftazidime by intravenous drip，conventional oxygen，acid-base imbalances correct and supportive treatment，the observation group was given Ambroxol Hydrochloride by intravenous drip on the basis treatment of the control group.The treatment effective rate，pathology of pneumonia，signs of improvement and incidence condition of adverse reaction between two groups were observed and compared.Result：The total effective rate of the observation group was 93.75%，which was significantly higher than 67.50% of the control group，the difference was statistically significant（ 字2=10.1063，P=0.0015）.The disappearing time of cough，fever reducing time，lungs elimination time，average stay time in the observation group were significantly shorter than those in the control group，the daily number of sputum suction in the observation group was significantly less than that of the control group，the differences were stat