丙型肝炎病毒细胞和动物模型的研究进展资料.doc

丙型肝炎病毒模型的研究进展摘要：丙型肝炎病毒（HCV）是造成慢性肝炎、肝硬化及肝癌的重要原因之一，目前全世界约有1.7亿人感染HCV。由于缺少有效的HCV细胞培养系统和小动物模型，人们对其生活周期、作用机制等仍不是很清楚，从而严重阻碍了HCV疫苗及治疗药物的开发与研制。本文就近几年在HCV模型方面的进展作一综述。 关键词：丙型肝炎病毒　细胞模型　动物模型 Progress in Establishment of HCV Model Abstract: Hepatitis C virus(HCV) is a major cause of chronic liver disease, such as chronic hepatitis, hepatic cirrhosis, hepatocelhlar carcinoma, with over 170 million persistently infected individuals worldwide. Lack of proper study models has brought difficulties in the study of the mechanism of viral infection, life cycle and pathogenic mechanism of HCV and also become the