名校医学微生物学31.pptVIP

A. Overview of diagnostic methods of virus infection In general, diagnostic tests can be grouped into 3 categories.: direct detection indirect examination (virus isolation) serological methods. Direct detection In direct examination, the clinical specimen is examined directly for the presence of virus particles, virus antigen or viral nucleic acids. Electron Microscopy morphology / immune electron microscopy Light microscopy for histological appearance - e.g. inclusion bodies Antigen detection with immunofluorescence, ELISA etc. Molecular techniques for the direct detection of viral gen