药物所研究生课件 蛋白质化学讲义.pptVIP

Stereo Structure Determination UV (Ultraviolet) spectroscopy CD (Circular Dichroism) Florescence IR (Infrared) and Raman spectroscopy AFM (Atomic Force Microscopy) ESR (Electron Spin Resonance) X-ray diffraction (crystallography) MS (Mass spectrometry) Multidimensional NMR (Nuclear Magnetic Resonace) spectroscopy Spectroscopic Methods in Structural Analysis of Peptides(1) UV: different absorbance strength and band wavelength for a-helix and b-sheet. Spectroscopic Methods in Structural Analysis of Peptides(2) CD: (1)190-240 nm: characteristic bands for peptide chain conformation (a- helix,