免疫球蛋白结构和功能关系.pptVIP

Immunoglobulin Structure-Function Relationship 免疫球蛋白的结构与功能的关系 Antibodies are Proteins that Recognize Specific Antigens 抗体能够特异性的识别抗原 Epitopes（抗原决定簇 ）: Antigen Regions that Interact with Antibodies Consequences of Antibody Binding抗体结合效应 CH3 CH2 Fb Fv Fv Fv Fb Fv Hinge Elbow CH3 CH2 Fb Fv Flexibility and motion of immunoglobulins 30 strongly neutralising McAb 60 strongly neutralising McAb Fab regions 60 weakly neutralising McAb Fab regions Human Rhinovirus 14 - a common cold virus 30nm Models of Human Rhinovirus 14 neutralised by monoclonal antibodies Electron micrographs of Antibodies and com