第2章立体化学原理重点.pptVIP

* * * * * * * * * * 2.12 构象分析 研究分子中优势构象的存在以及构象对分子的物理性质和化学性质 的影响，称为构象分析(conformational analysis)。 * * * 构象效应 由于构象不同而对分子的化学性质所产生的不同影响统称构象效应。 * 几个概念： 去对称化 * 有机催化 * * * 动力学拆分 * Dynamic kinetic resolution (DKR) is when the starting material can racemise under the reaction conditions, since this process is an equilibrium, with the faster reacting enantiomer being continually removed from the system, the major product of the reaction can exceed the previous maximum yield of 50%. DKR provides the possibility of up to 100% yield, provided the racemisation is much faster than the irreversible re