Narcotrend监测在无痛取卵术中的应用.docVIP

Narcotrend监测在无痛取卵术中的应用 黄艰 文欣荣 崔剑 鲁开智 摘要 目的：探讨Narcotrend监测在无痛取卵术中的应用。方法：无痛取卵患者60例，ASAⅠ～Ⅱ级，年龄22～43岁，体重42～85kg，随机分为3组，每组20例：每组患者均血浆靶控输注（TCI）瑞芬太尼2.0ng/ml，A组TCI丙泊酚1.5～2.0μg/ml调整NI至B2-C0，B组TCI丙泊酚2.0～2.5μg/ml调整至C1-C2，C组TCI丙泊酚2.5～3.0μg/ml调整至D0-D1，术毕给予帕瑞昔布钠40mg静脉注射。记录各组血流动力学参数，手术中异丙酚诱导时间、苏醒时间、用药量，体动次数、药物追加次数、不良反应以及术后半小时VAS评分。结果：三组患者基本情况、血流动力学参数、麻醉不良反应、术后半小时VAS评分无统计学差异。与A组相比，B、C组诱导时间缩短、用药量增多，术中体动次数，药物追加次数减少；与B组相比，C组术中体动次数，药物追加次数，术中知晓率降低（P0.05）。结论：采用靶控瑞芬太尼2.0ng/ml与异丙酚2.5～3.0μg/ml联用，维持NI值64～47能满足无痛取卵的麻醉深度，同时麻醉不良反应少。 关键词 无痛取卵 narcotrend 异丙酚 瑞芬太尼 The Application of Narcotrend-assisted Monitor in Patients during Painless Vaginal Egg Retrieval HuangJian WenXinrong CuiJian LuKaizhi Abstract Objective: To investigate the application of narcotrend-assisted monitor in patients during painless vaginal egg retrieval. Methods: A total of 60 patients undergoing painless vaginal egg retrieval, with ASA Ⅰ～Ⅱ, aged 22～43 , 42～85kg , were randomly divided into 3 groups: each patient was received plasma target controlled infusion (TCI) of remifentanil at 2.0ng/ml; Group A received plasma TCI propofol at 1.5～2μg/ml and NI was adjusted to B2～C0; Group B received plasma TCI propofol at 2～2.5μg/ml with NI of C1～C2;Group C received plasma TCI propofol at 2.5～3μg/ml with NI of D0～D1. After operation, intravenous administration of parry celebrex sodium was controlled to 40mg. The observation targets, including hemodynamic parameters, recovery time, the dosage of propofol, body dynamic response, additional drug, adverse reaction and VAS score were recored after operation half an hour. Results: There were no significant differences in the basic situation, hemodynamic parameters, adverse reactions and VAS score among the three groups. However, compared with group A, the induction time in group B and C was shorter, and the rate of body dynamic response as well as the additional drug used in group B and C were decreased. Compared with group B, the rate of body dynamic response, the additional drug an