加用三金片治疗小儿急性肾小球肾炎临床研究.docVIP

加用三金片治疗小儿急性肾小球肾炎的临床研究.txt有没有人像我一样在听到某些歌的时候会忽然想到自己的往事_______如果我能回到从前，我会选择不认识你。不是我后悔，是我不能面对没有你的结局。 加用三金片治疗小儿急性肾小球肾炎的临床研究 更新日期：2009-03-31 点击： 陈孝银　沈强 　　摘要　目的：观察加用三金片对小儿急性肾小球肾炎的治疗作用。方法：在临床上，加用三金片治疗小儿急性肾小球肾炎40例(观察组)，并与西药组38例及正常对照组40例对比。结果：急性肾小球肾炎患者(包括观察组及西药组)脂质过氧化物(LPO)、谷胱苷肽过氧化物酶(GSH-Px)与正常组比较有显著性差异(P＜0.001)，而超氧化物岐化酶(SOD)则无显著性差异(P＞0.05)。经治疗后LPO降低，GSH-Px增高，观察组疗效优于西药组(P＜0.05)。患儿前列腺素稳定代谢产物6-K-PGF1a降低，TXB2下降，TXB2/6-K-PGF1a比值升高，与正常组相比具有显著差异(P＜0.001)。治疗后TXB2下降，6-K-PGF1a升高，TXB2/6-K-PGF1a下降，观察组疗效优于西药组(P＜0.01)。此外，观察组患儿血尿和蛋白尿阳转率也明显优于西药组。结论：提示观察组用药具有较强的抗自由基及消除炎性致病因子能力，并且对肾功能有良好的保护作用。 　　关键词　急性肾小球肾炎；自由基；脂质过氧化物；超氧化物岐化酶；谷胱甘肽过氧化物酶；血栓素B2；6-酮-前列腺素F1a Clinical Study on the Treatment of Infantile Acute Glomerulonephritis with Additional Application of San Jinpian Chen Xiaoyin （Medical College, Jinan Unniversity 510632） Sheng Qiang （The 1st Affiliated Hospital, Guangzhou University of TCM 510407） 　　Abstract Purpose：To observe the curative effect of the additional use of San Jinpian on infantile acute glomerulonephritis(IAG). Methods: Clinically, 40 cases with IAG ( the control group) were treated with the additional use of San Jinpian to compare its effect with 38 cases treated with only western medicine(WM group) and with 40 cases in the control group. Results: When compared with the control group, the observation group and WM group showed a significant difference in LPO and GSH-Px( P0.001), while there was no significant difference in SOD(P0.05). After the treatment, LPO became lower but GSH-Px increased, with the observation group achieving better curative effects than WM group (p0.05) 6-K-PGF1a and TXB2 became lower and the ratio of TXB2 to 6-K-PGF1a was increased with a very significant difference between the observation group and the control group (P0.001). After the treatment, TXB2 became lower while 6-K-PGF1a higher and the ratio of TXB2 to 6-K-PGF1a was lower, with the better effect shown in the observation group than in WM group (P0.01). In addition, the transitional rate of hematu