不同CD4T细胞亚群对动脉粥样硬化斑块易损性和斑块破裂的影响及其机制研究.pdf

目录中文摘要?????????????????????????????．．?第一部分不同???赴?侨憾远?鲋嘌?不?呖橐姿鹦院桶呖槠屏训挠跋?研究动脉粥样硬化斑块易损和斑块破裂的动物模型???????动脉粥样硬化斑块易损性和斑块破裂的发生免疫学机制??????研究目的???????????????????????????动脉粥样硬化斑块破裂小鼠模型的建立??????????????不同???赴?侨河氚呖槠屏训墓叵怠????????????英文摘要???????????????????????????符号说明???????????????????????????正文???????????????????????????吾???????????????????????????一、动脉粥样硬化易损斑块的特性??????????????????二、三、四、材料???????????????????????????方法???????????????????????????结果???????????????????????????讨?亍???????????????????????????二、??、??蚑??诙?鲋嘌?不?呖槠屏阎邪缪莶煌?巧?ⅰ????三、??及其主要效应分子在促进动脉粥样硬化斑块破裂中发挥更重要的作用??????????????????????????小结???????????????????????????第二部分?一??远?鲋嘌?不?呖橐姿鹦院桶呖槠屏训淖饔眉盎?蒲芯?一、??的特性及其在疾病中的作用????????????????．?二、??／???胶庠诙?鲋嘌?不?膊≈械淖饔谩????????三、细胞凋亡在动脉粥样硬化疾病中的作用???????????．??日?刖—?—??一—?—?甃 四、外源性?．?体外处理可以增强平滑肌细胞的凋亡?????????????一?与动脉粥样硬化斑块的易损性和斑块的破裂???????··?附件?⑽奈恼???????????????????????????·??材料???????????????????????????方法???????????????????????????结果???????????????????????????一、外源性?．?对动脉粥样硬化斑块易损性的影响??????????二、外源性?．?干预后对小鼠动脉粥样硬化斑块破裂的影响?????·?三、外源性?．?干预不同时间后对外周???赴?侨旱挠跋臁????????讨论???????????????????????????二、?．?诱导的平滑肌细胞凋亡与斑块的易损性和斑块的破裂．．．．．．?小结???????????????????????????附图???????????????????????????参考文献???????????????????????????致谢???????????????????????????攻读博士学位期间发表论文及编著目录???????????????··????? 甌??甌????????????????????????????????????????··????????????????????????????????··????????????????????????????????????????????????????????一??????????????????????????????ぁ?????????????????????????????????????????????????????????··········································································????????????ぁ???????????????????????????????????????????ぁ??????ぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁ?··‘······························??????·??????????????????ぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁ???甈???????????????????????????????ぁ?????????????·············································································??甌?????一??????ぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁぁ