结核病潜伏期要点.ppt

流式网络课堂第五课 流式新闻 苏州跃亚技术部 孟琳 2011-11-30 利用CD4+TNF-a+细胞群体鉴别结核病的潜伏期和活动期 latent Mtb infection active tuberculosis disease The frequency of single-positive TNF-α–producing CD4+ T cells was higher in individuals with active disease the cutoff of 37.4% of single-positive TNF-α 结论： The proportion of TNF-α single-positive Mtb-specific CD4+ T cells, and particularly the cutoff at 37.4%, could discriminate between latent infection and active disease. The sensitivity and specificity of the flow cytometry–based assay were 67% and 92%, respectively, the positive