电针对功能性腹泻模型大鼠空肠组织Ckit蛋白表达影响.pdf

Effect of E l ectroacupuncture on the express i on of C—k i t Drote i n i n the ie iunum t i ssue funct i ona l d j ar rhea i n ratsO l I ne．Ie．JUnU l SSU tU C l O a I n I ℃S Abstract Objective：Tb explore tlle parameters in certain electrical stimulation of din’erent combinations of points，me model rat j ejuImm够rosirle l【inaLse rec印tor expression arld dis劬ution of C-妞proteiIl(C一㈨content by detec血g胁Ctio砌di撕hea，obseⅣed jejllIlum chaIlge between interstitial cells(C萄a1)m rat jejunum，tlle study of acupuncture on f．unctional diarrhea screelling pro伊锄compatibilit)，and optiIllization of cliIlical acupuncture仃eatment． Methods：60 SD rats，in wliich 10 aS a coIl仃ol group，10 aS me teInperature of water fed 伊oup，me remailling 40 seIma decoction gaVage using replication胁ctional di撕hea rnodel，modeling a big success rats were ralldomly diVided into f．our groups，inCluding t11e collection of$acupoints吮atment group(Quclli ShaIl西uXu)，u11it acupoints treatment黟oup(Tiallshu DaChallgshu)，plus sets per u11it acupoints仃eannent and control model掣oup(no仃eatIllent伊oup)．A舭r mree tre她ent groups a course of acupull叽玳 仃ea缸nent(10)ends，the interCeption of jejurlal tissue lcm，谢tll chaI坞es detected by W．estem blot C-尉t protein expression，detection effect． Results：T11e expression of rat jejuIlum model contr01 group C-飚t si鲥ficamly lligher tllan tlle control掣oup(PO．01)；ARer acupuncture仃eatment，witll me improVement of dia盯hea，rat jejuIl啪C—Kit protein content decreaSed mere、vaS si嘶6c觚t di位renCe(P 0．05)after tI。eatment compared witll model伊oup．Among tllem，t11e rat j甸unum CHEW砒N aCupoints仃eatIllent野oup C-瞄t protein eXpression、ⅣaS si蛐fic趾tly reduced compared晰t11 me con仃ol group，tllere waS a si嘶fic趾t di髓rence(P0．0 1)； unit plus Sets per tre她ent group acupoints caIl si91li丘cantly 10wer j句unum compared 诚m me model group，t11ere waus a si嘶ficant di髓rence(PO．01)． Conclusion：EA仃ea缸nent of劬ctional dianmea rat model h舔obVious t11erapeutic e行ect and me e彘ct is sigllificant；abnomalities aIld C-Kjt proteiIl eXpression