血小板输注效果与血液免疫学课件.pptVIP

部分HLA抗原间存在一些相同的表位 国外血小板HLA- CREGs 配合输注 Quality of the HLA-A -B locus match determines outcome [RECIPIENT: A1 A2 B7 B8] A HLA identical all 4 loci [A1 A2 B7 B8] BU All loci identical, only 3 Ag’s detected [A1 A1 B7 B8] B2U All loci identical, only 2 Ag’s detected [A1 A1 B8 B8] BX 3 loci identical, 4th cross-reactive [A1 A11 B7 B8] BUX 3 Ag’s, 2 identical, 3rd X-reactive [A1 A11 B8 B8 ] B2X 2 loci identical, 2 X-reactive [A1 A11 B7 B60] C one locus mismatched [A1 A32 B7 B8] D two or more loci mismatched [A1 A32 B7 B60] R Random HLAMatchmaker的原理 Duquesnoy （2001 ）发明了H