pH响应性聚合物胶束及其在抗癌药物给药系统中的研究进展.docVIP

pH响应性聚合物胶束及其在抗癌药物给药系统中的研究进展 摘要：聚合物纳米粒作为一种有效的药物运送载体已经受到广泛的关注，具有环境响应性的聚合物胶束的制备及应用是目前引人瞩目的研究方向。本文综述了pH值响应性的聚合物胶束的两种主要制备策略，并介绍了其在抗癌药物给药系统中的应用。 关键词：聚合物胶束；pH响应性；抗癌药物；载体 Advance in pH-responsive polymeric micelles as delivery system for anticancer drugs Abstract: Polymeric nanoparticles as a kind of effective drug carrier have been widely concerned on. Particularly, more attentions have been paid to the applications of pH-responsive polymeric micelles. This paper reviews recent progress in synthetic strategy of polymeric micelles with pH-responsive structure and its applications as delivery system