维持性血液透析患者应用不同血液净化方式对残余肾功能影响的临床意义分析.docVIP

维持性血液透析患者应用不同血液净化方式对残余肾功能影响的临床意义分析 　　【摘要】目的：研究分析采用不同的血液净化额方式对于维持性血液透析的患者的残留肾功能的影响。方法：选取本院自2012年3月至2015年3月间收治入院的进行血液透析的尿毒症患者35例，随机将其分为治疗组1和治疗组2，治疗组1采用HFHD（高通量血液透析），共有患者18例，采用Hi15透析器；观察组2采用LFHD（低通量血液透析），有患者17例采用Lops15透析器。两组患者分别透析3个月后，对照观察两组患者治疗前后的残余肾功能的情况。结果：经过各自的透析治疗后，两组患者均较治疗前肾功能有所降低，但治疗组1的下降幅度明显较治疗组2的下降幅小，且高通量血液透析患者体内血磷浓度、血脂浓度以及β2微球蛋白的含量显著低于低通量血液透析的患者。结论：研究表明，对维持性血液透析的患者无论采取何种透析方式，其参与肾功能均会下降，较低通量透析而言，高通量透析患者的参与肾功能相对下降幅度小，由此看来，采用高通量的血液透析明显对参与肾功能有保护作用，同时还能有效降低患者的血脂浓度、血磷浓度及β2微球蛋白的功能。值得临床推广应用。 　　【关键词】尿毒症；血液透析；残余肾功能；临床疗效分析 　　Abstract Objective： To study the effect of different blood purification methods on residual renal function in patients with maintenance hemodialysis. Method： Selected in our hospital from March 2012 to 2015 March admitted for hemodialysis in uremic patients 35 cases randomly divided into the treatment group 1 and treatment group 2， treatment group 1 and adopt the HFHD （high flux hemodialysis）， 18 patients were， the dialyzer Hi15； observation group 2 with lfhd （low flux hemodialysis）， 17 cases of patients with the Lops15 dialyzer. Two groups of patients were treated with 3 months after dialysis， and the residual renal function of the two groups were observed before and after treatment. Results： After treatment， the renal function of the two groups were lower than before treatment， but the decrease of 1 in the treatment group was significantly lower than that in the treatment group 2， and high flux hemodialysis patients were significantly lower than those in the low flux hemodialysis patients. Conclusion： The study showed that the patients with maintenance hemodialysis in the way of dialysis， the involvement of renal function decline， compared with the low flux dialysis， high flux dialysis patients in the relatively small decline in renal function， thus it seems that the use of high flux hemodialysis significantly to participate in the protection of renal function， but also can effectively reduce the blood lipid concentration， serum phosphorus