COPD发展中CT测量与肺气肿的相关性.docVIP

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COPD发展中CT测量与肺气肿的相关性.doc

COPD发展中CT测量与肺气肿的相关性   [摘要] 目的 探讨慢性阻塞性肺疾病(COPD)发展中肺气肿变化规律及其CT测量量化指标与肺气肿的相关性。方法 选取我院2011年5月~2013年5月收治的慢性阻塞性肺疾病(COPD)患者中100例作为观察组,同期选择100例健康者作为对照组,并采用CT测量两组患者肺容量、肺气肿容量、肺气肿指数变化情况。 结果 观察组的肺容量、肺气肿容量、肺气肿指数均显著高于对照组,差异均有统计学意义(均P0.05)。在观察组中,不同肺功能程度患者在肺容量、肺气肿容量、肺气肿指数差异均有统计学意义(均P0.05),且随着肺功能下降程度的加重,各项量化指标均呈现不断增加的趋势。 结论 临床可以利用CT测量量化指标来监测慢性阻塞性肺疾病(COPD)发展过程中肺气肿的变化情况,且随着COPD发展,肺气肿程度不断加重,其变化情况和患者肺功能分级之间具有一定的相关性。   [关键字] 慢性阻塞性肺疾病(COPD);肺气肿;CT   [中图分类号] R816.4 [文献标识码] A [文章编号] 1673-9701(2015)13-0019-04   [Abstract] Objective To explore the changes discipline of emphysema in the development of chronic obstructive pulmonary disease(COPD) and relativity of CT quantitative index measurement and emphysema. Methods A total of 100 cases of patients with chronic obstructive pulmonary disease (COPD) in our hospital from May 2011 to May 2013 were selected, and 100 cases of healthy people were randomly selected as control group,and the used of CT in patients with lung volume measurement groups, emphysema capacity, emphysema index changes. Results The lung capacity, emphysema, pulmonary emphysema capacity index of the observation group were all significantly higher than the control group (all P0.05). The differences of lung capacity, emphysema, pulmonary emphysema capacity index of pulmonary function between patients with different degrees in the observation group were all significantly (all P0.05).And all of the quantitative indicators increased with the increase of the degree of decline of lung function. Conclusion The clinical can use CT quantitative indicators to monitor chronic obstructive pulmonary disease (COPD) changes in the development of emphysema, and with the development of COPD, emphysema degree is increasing, there is a certain correlation between the changes and pulmonary function grades of patients.   [Key words] Chronic obstructive pulmonary disease (COPD); Emphysema; CT   慢性阻塞性肺疾病(COPD)是一种慢性呼吸系统疾病,发病率和病死率都较高,对人体健康危害极大[1,2]。肺气肿是COPD临床十分重要的特征,利用CT扫描方式,特别是CT肺功能定量测量,不仅可得到

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