口服醋酸甲羟孕酮片与宫内放置节育器预防术后子宫内膜息肉复发的效果比较.docVIP

口服醋酸甲羟孕酮片与宫内放置节育器预防术后子宫内膜息肉复发的效果比较 　　[摘要] 目的 比较宫腔镜电切术后口服醋酸甲羟孕酮片与宫内放置节育器预防子宫内膜息肉复发的临床效果。 方法 选取本院2010年8月～2013年6月的113例子宫内膜息肉患者作为研究对象，采用随机数字表法分为宫腔镜电切术后口服醋酸甲羟孕酮片组（57例）和宫内放置节育器组（56例）。比较两组的术前、术后子宫内膜厚度及息肉复发率。 结果 宫内放置节育器组术后半年、1年和1.5年的子宫内膜厚度显著薄于术前及醋酸甲羟孕酮片组，差异有统计学意义（P0.05）。宫内放置节育器组的复发率显著低于口服醋酸甲羟孕酮片组，差异有统计学意义（P0.05）。 结论 宫腔镜子宫内膜息肉电切术后宫内放置节育器可有效预防子宫内膜息肉复发。 　　[关键词] 口服醋酸甲羟孕酮片；曼月乐；宫腔镜；子宫内膜息肉复发 　　[中图分类号] R711.7 [文献标识码] A [文章编号] 1674-4721（2015）09（a）-0102-03 　　[Abstract] Objective To compare the clinical effect of oral administration medroxyprogesterone acetate tablets after hysteroscopy electrosurgical and application of intrauterine device after hysteroscopy electrosurgical in the preventing recurrence of endometrial polyps. Methods 113 endometrial polyps （EP） patients from August 2010 to June 2013 in our hospital were selected and divided into the oral administration medroxyprogesterone acetate tablets after hysteroscopy electrosurgical group （n=57） and the application of intrauterine device group （n=56） according to random number table method.Endometrial thickness before and after surgery，and recurrence rate of polyp between in two groups was compared. Results Endometrial thickness in the application of intrauterine device group at the time of half a year，one year and 1.5 years was slighter than that before surgery and the oral administration medroxyprogesterone acetate tablets group，with significant difference（P0.05）.Recurrence rate of polyp in the application of intrauterine device group was lower than that in the oral administration medroxyprogesterone acetate group，with significant difference（P0.05）. Conclusion Application of intrauterine device after hysteroscopy electrosurgical can effectively prevent EP recurrence. 　　[Key words] Oral administration medroxyprogesterone acetate tablets；Mirena；Hysteroscopy；Recurrence of endometrial polyps 　　子宫内膜息肉（endometrial polyps，EP）是导致女性异常子宫出血和不孕症的常见疾病，近年来其发生率呈上升趋势，对女性的健康造成较大伤害。临床上EP的诊治主要依据宫腔镜及病理，目前应用较广泛的手术方式是宫腔镜EP电切术（transit coop