去氧孕烯炔雌醇片治疗青春期无排卵性功能失调性子宫出血的临床效果.docVIP

去氧孕烯炔雌醇片治疗青春期无排卵性功能失调性子宫出血的临床效果 　　[摘要] 目的 观察去氧孕烯炔雌醇片治疗青春期无排卵性功能失调性子宫出血（功血）的临床效果。 方法 选取本院2009年1月～2014年12月收治的120例青春期功血患者的临床资料，将患者随机分为观察组与对照组，各60例。观察组患者采用去氧孕烯炔雌醇片进行治疗，对照组患者采用己烯雌酚联合醋酸甲羟孕酮片进行治疗，记录并比较两组患者的控制出血时间、完全止血时间以及临床效果。 结果 观察组的控制出血时间为（25.61±11.23）h，完全止血时间为（53.06±20.87）h，均明显短于对照组的（36.40±14.57）、（77.55±21.81）h（P0.05）；观察组的总有效率为100.0%，明显高于对照组的90.0%（P0.05）。 结论 去氧孕烯炔雌醇片治疗青春期无排卵性功血的止血效果显著，不良反应少，值得临床推广应用。 　　[关键词] 去氧孕烯炔雌醇片；青春期无排卵性功能失调性子宫出血；临床效果 　　[中图分类号] R711.52 [文献标识码] A [文章编号] 1674-4721（2015）07（b）-0130-03 　　[Abstract] Objective To observe the clinical effect of desogestrel and ethinylestradiol tablet in the treatment of anovulatory dysfunctional uterine bleeding in puberty. Methods From January 2009 to December 2014，clinical data from 120 patients with dysfunctional uterine bleeding in puberty admitted into our hospital were selected and evenly divided into observation group and control group in random.In observation group，desogestrel and ethinylestradiol tablet was applied for the treatment，while in control group，diethylstilbestrol combined with medroxyprogesterone acetate tablet was adopted in the treatment. The time of controlling bleeding，totally stanching bleeding，and clinical effect between two groups was recorded and compared respectively. Results The time of controlling bleeding and totally stanching bleeding in observation group [（25.61±11.23） h and （53.06±20.87） h] was obviously shorter than that of control group [（36.40±14.57） h and （77.55±21.81） h] respectively （P0.05）.In observation group，the total effective rate （100.0%） was obviously higher than that of control group （90.0%） （P0.05）. Conclusion Desogestrel and ethinylestradiol tablet can obtain a remarkable hemostatic effect treating anovulatory dysfunctional uterine bleeding in puberty and has less adverse reaction， which should be promoted and applied in clinic. 　　[Key words] Desogestrel and ethinylestradiol tablet；Anovulatory dysfunctional uterine bleeding in puberty；Clinical effect 　　功能性子宫出血（功血）