呼吸内科下呼吸道感染病原菌及耐药探讨.docVIP

呼吸内科下呼吸道感染病原菌及耐药探讨 　　【摘要】 目的：分析呼吸内科下呼吸道感染病原菌及耐药。方法：收集2013年1月-2014年1月本院收治的120例下呼吸道感染患者的临床资料，分析痰培养结果及药敏试验结果，并探讨患者病原菌分布情况和耐药性。结果：革兰阴性菌所占百分率明显高于革兰阳性球菌和真菌，差异有统计学意义（P0.05）；革兰阴性杆菌对磺胺甲?f唑耐药率明显高于革兰阳性球菌，敏感率明显低于革兰阳性球菌，差异有统计学意义（P0.05）；对阿莫西林、庆大霉素、左氧氟沙星、亚胺培南耐药率明显低于革兰阳性球菌，敏感率明显高于革兰阳性球菌，差异有统计学意义（P0.05）。结论：呼吸内科下呼吸道感染病原菌大多为革兰阴性菌，在临床中必须根据患者药敏试验情况，给予患者提供合理的用药方案，以改善患者预后情况。 　　【关键词】 呼吸道感染； 病原菌； 耐药性 　　Exploration of the Pathogenic Bacteria and Drug Resistance for Patients with Lower Respiratory Infection/GUO Bao-ming.// Medical Innovation of China，2015，12（24）：099-101 　　【Abstract】 Objective：To explore the pathogenic bacteria and drug resistance for the patients with lower respiratory infection.Method：120 cases of lower respiratory infection were analyzed， the results of sputum culture and drug sensitive test were analyzed. The pathogenic bacteria distribution and drug resistance were analyzed.Result：The rate of gram negative bacteria were higher than gram-positive bacteria and fungus， with significant difference（P0.05）.The drug resistance rate for sulfamethoxazole with gram negative bacteria were higher than gram-positive bacteria，with significant difference（P0.05），the susceptibility were lower than gram-positive bacteria， with significant difference（P0.05）； The drug resistance rate of amoxicillin， gentamicin， levofloxacin，imipenem with gram negative bacteria were lower than gram-positive bacteria，with significant difference（P0.05），the susceptibility were higher than gram-positive bacteria，with significant difference（P0.05）. Conclusion：Most of respiratory medicine lower respiratory infection pathogens in gram-negative bacteria， in the clinical drug susceptibility test must be based on patients，provide a reasonable regimen for patients，in order to improve patients’ prognosis. 　　【Key words】 Respiratory tract infection； Pathogenic bacteria； Drug resistance 　　First-author’s address：The People’s Hospital of De’an，De’an 330400，China 　　doi：10.3969/j.issn.1674-4985.2015.24.036 　　下呼吸道感染是