药师干预模式对服用华法林患者的依从性、疗效和生活质量的影响.docVIP

药师干预模式对服用华法林患者的依从性、疗效和生活质量的影响 　　【摘要】 目的：研究临床药师干预模式对华法林患者依从性、临床疗效以及生活质量的影响。方法：选取本院2013年6月-2014年6月收治的60例慢性房颤患者作为研究对象，按出院顺序随机分为观察组与对照组，每组各30例。观察组采用临床药师干预模式，对照组无药师参与，对比两组患者用药依从性、疗效以及生活质量的差异。结果：观察组的总依从性为86.67%，明显高于对照组的56.67%，两组比较差异有统计学意义（P0.05）；观察组血栓出现率以及总出血率分别为0、6.67%，明显低于对照组的13.33%和26.67%，两组比较差异有统计学意义（P0.05）；观察组出院1年后各项评分均显著高于对照组，差异有统计学意义（P0.05）。结论：对接受华法林治疗患者采取药师干预模式可以提高其用药依从性以及疗效，并提高患者的生存质量，具有较高的临床推广价值。 　　【关键词】 临床药师干预模式； 华法林； 依从性； 疗效； 生活质量 　　The Influence of Clinical Pharmacist Interventions on the Compliance，Efficacy and Life Quality of Taking Warfarin/WU Shi-quan，TAN Cai-hong，DONG Yu-hua.//Medical Innovation of China，2015，12（16）：016-018 　　【Abstract】 Objective：To study the influence of clinical pharmacist intervention model on compliance，clinical efficacy and life quality of warfarin.Method：60 patients with chronic AF were selected in our hospital from June 2013 to June 2014 as the research object，and were divided into observation group and control group according to the discharge order，30 cases in each group.The observation group was treated with clinical pharmacist intervention，control group was treated without pharmacists，drug compliance，efficacy and life quality of two groups were compared.Result：The total compliance of the observation group was 86.67%，significantly higher than the control group of 63.33%，the difference was statistically significant（P0.05）； occurrence rates of thrombosis and bleeding rates of observation group were 0 and 6.67%，significantly lower than control group of 13.33% and 26.67%，the differences were statistical significance（P0.05）； when the observation group discharged after 1 years，the scores were significantly higher than those in the control group，the differences were statistically significant（P0.05）.Conclusion：Pharmacists intervention mode to accept warfarin treatment can improve the medication compliance and curative effect，improve the quality of life of patients，has high clinical value. 　　【Key words】 Clinical pharmacist inter