曲美他嗪治疗老年缺血性心肌病临床疗效观察.docVIP

曲美他嗪治疗老年缺血性心肌病临床疗效观察 doi：10.3969/j.issn.1007-614x.2014.22.40 摘要目的：探讨曲美他嗪治疗老年缺血性心肌病的临床疗效。方法：2008-2013年收治缺血性心肌病老年患者92例，随机分为观察组和对照组，各46例，所有患者均先采用常规基础治疗，观察组在此基础上联用曲美他嗪治疗。结果：两组病情均有一定程度的改善，观察组显效22例，有效18例，无效6例，有效率86.96%。对照组显效19例，有效16例，无效11例，有效率76.09%。结论：在治疗老年缺血性心肌病时，在常规治疗的基础上，联用曲美他嗪以进一步改善治疗老年缺血性心肌病的效果较为显著，对患者病情的改善疗效肯定。 关键词老年；缺血性心肌病；曲美他嗪 Clinical curative effect observation of trimetazidine in the treatment of senile ischemic cardiomyopathy Xie De The Traditional Chinese Medicine Hospital of Qingtongxia City，Ningxia 751600 AbstractObjective：To investigate the clinical efficacy of trimetazidine in the treatment of elderly patients with ischemic cardiomyopathy.Methods：92 cases with ischemic cardiomyopathy were selected from 2008 to 2013.They were randomly divided into the observation group and the control group with 46 cases in each.All cases were first with conventional treatment.The observation group were given trimetazidine based on the control group.Results：In the observation group，22 cases were markedly effective；18 cases were effective；6 cases were invalid；the efficiency rate was 86.96%.In the control group，19 cases were markedly effective；16 cases were effective；11 cases were invalid；the efficiency rate was 76.09%.Conclusion：In the treatment of senile ischemic cardiomyopathy，on the basis of conventional therapy，the effect of combined with trimetazidine to further improve the treatment of aged patients with ischemic cardiomyopathy is obviously，and it can improve the curative effect of the patient’s condition. Key wordsThe elderly；Ischemic cardiomyopathy；Trimetazidine 冠状动脉动力性和（或）阻力性因素引起的冠状动脉狭窄或闭塞性病变是缺血性心肌病的基本病因。老年缺血性心肌病是指由于长期心肌缺血导致心肌局限性或弥漫性纤维化，从而产生收缩和（或）舒张功能受损，引起心脏扩大或僵硬、充血性心力衰竭、心律失常等一系列临床表现的综合征。与原发性充血型心肌病的临床表现相似，但在本质上ICM是一种由冠状动脉供血减少引起的严重心肌功能失常。其主要病因是患者长期心肌缺血或发生心梗后引发非室壁瘤样，并慢行的心功能不全，此种疾病的主要临床表现为心脏扩大、心室壁变薄，慢性充血性心衰、顽固性心律失常等。因此，临床医生需要及时准确地诊断和对症治疗此类疾病，以促进患者病情的康复，降低患者死亡率[1]。2008-2013年收治缺血性心肌病老年患者92例，采用在常规治疗的基础上，联用曲美他嗪观察对缺血性心肌病老年患者心功能的影响和安全性，并回顾性分析其临床治疗效果，现报告如下。 资料与方法 2008-2013年