TCellDevelopment-TheUniversityofVermont.pptVIP

Principles of ImmunologyImmunodeficiency4/20/06 ”Wise people talk because they have something to say; fools, because they have to say something” Plato Word/Terms List AIDS SCID Primary immunodeficiency Secondary immunodeficiency Immunodeficiency Primary-usually genetic, congenital Secondary-Acquired Mechanisms of Immunodeficiency Loss or reduction of: Cell type Cell numbers Cell function Loss of Cell Function Receptors Cell signaling Cytokine production Ig production Co stimulation impairment Intracellular killing Extravasation impairment Primary Immunodeficiency Myeloid lineage