28SleepLetsBrainFileMemor.docVIP

28 Sleep Lets Brain File Memories To sleep. Perchance to file? Findings published online this week by the Proceedings of the National Academy of Sciences further support the theory that the brain organizes and stows memories formed during the day while the rest of the body is catching zzzs. Gyorgy Buzsaki of Rutgers University5 and his colleagues analyzed the brain waves of sleeping rats and mice. Specifically, they examined the electrical activity emanating from6 the somatosensory neocortex an area that processes sensory information and the hippocampus, which is a center for learning and memory. The scientists found that oscillations in brain waves from the two regions appear to be intertwined. So-called sleep spindles bursts of activity from the neocortex were followed tens of milliseconds later by beats in the hippocampus known as ripples. The team posits that this interplay between the two brain regions is a key step in memory consolidation. A second study, also published online this week by the Proceedings of the National Academy of Sciences, links age-associated memory decline to high glucose levels. Previous research had shown that individuals with diabetes suffer from increased memory problems. In the new work, Antonio Convit of New York University School of Medicine and his collaborators studied 30 people whose average age was 69 to investigate whether sugar levels, which tend to increase with age, affect memory in healthy people as well. The scientists administered11 recall tests, brain scans and glucose tolerance tests, which measure how quickly sugar is absorbed from the blood by the bodys tissues. Subjects with the poorest memory recollection, the team discovered, also displayed the poorest glucose tolerance. In addition, their brain scans showed more hippocampus shrinkage than those of subjects better able to absorb blood sugar. Our study suggests that this impairment12 may contribute to the memory deficits13 that occur as people age. Convit says.