Chapter29Arbovirus(Arthropod-bornevirus).pptVIP

Chapter 23  Arbovirus of prevalence in China ---classified as Flavivirus ? JEV-infection ? Asymptomatic infection ? Abortive infection ? Cause epidemic encephalitis B (0.1%) 3.Laboratory Diagnosis ? Isolation of virus (cell culture) ? Serological diagnosis 1.Biological properties ?Dengue virus -infection ? route of transmisson ? primary infection→dengue fever ? reinfection→dengue hemorrhagic fever(DHF) or dengue shock syndrome (DSS) ? pathogenesis of DHF/DSS:ADE(antibody-dependent enhancement) 3