颗粒胶囊骨疏康解答.ppt

骨质疏松症：市场潜力巨大 9,000 10,000 16,000 单位：万人 原发性骨质疏松人群 继发性骨质疏松人群 骨量减少人群 骨疏康：目标科室 A级: 骨科,中医科,老年科 B级：内分泌,妇产科,肾内科 C级：康复科,疼痛科 骨疏康的支持平台是什么？ 骨疏康的三大平台 啊中国健康促进 基金会 骨质疏松专项基金 管理委员会 啊中国药学发展奖 康辰骨质疏松医药研究奖 （HOMA奖） 2000～2011 中国骨质疏松论坛 讨 论 ——最平衡双补的壮骨中药 * * 通常发生的这几种骨质疏松性骨折中： 前臂远端的骨折只有短期后果， 椎体骨折引起的并发症因骨折次数不同而不同； 髋骨骨折会造成更大的损害——不仅家庭和社会，需要承受巨大的经济负担，而且高达1/3的髋骨骨折病人生活完全不能自理，许多人永久残废，生活质量严重受损。 新加坡的一项研究数据表明，髋骨骨折一年后死亡率达到26%； 即使存活的患者做了置换手术，术后2-3年仍旧存在稳定性的问题…… * 骨质疏松症(osteoporosis)是以骨强度下降和骨折危险性增加为特征的一种全身性骨骼疾病。 骨质总量的减少和骨吸收大于骨形成，骨的脆性增加，“无外力骨折” * These images illustrate the microarchitecture of vertebrae of normal bone, osteoporosis and severe osteoporosis. In the normal bone, note the perpendicular orientation between the horizontal and vertical trabeculae. This interconnectivity of the three-dimensional lattice of the trabeculae makes the vertebral bodies particularly well suited to support compressive loads. In the osteoporotic vertebrae, one sees loss of connectivity, with interrupted or truncated rods, and thinning of trabecular plates. Note that the loss of horizontal or lateral struts occurs before loss of vertical struts, resulting in reduced load-bearing capacity, decreased bone strength and a greater susceptibility to fracture. This helps us understand why the definition of osteoporosis includes a reference to both a loss in mass or bone density as well as microarchitectural deterioration. * * Whether considering postmenopausal or age related osteoporosis, the magnitude of bone loss can be evaluated by histomorphometry: Cortical bone: measure thickness and porosity Trabecular bone measure: volume of trabecular bone trabecular thickness inter trabecular distance connectivity * * 中医学有肾主骨的理论，骨质疏松症的中医学病因在于肾虚，同时合并脾肾双虚。 * * * Practically, the suspicion of osteoporosis is often made by the doctor due to a fracture, or reduction of height of the patient. The doctor will also evaluate the risk factors and make a clinical exam. But the confirmed diagnosis will be made by the measurement of the