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Chapter 15 The Chromosomal Basis of Inheritance Lecture Outline Overview: Locating Genes Along Chromosomes Today we know that genes—Gregor Mendel’s “hereditary factors”—are located on chromosomes. A century ago, the relationship between genes and chromosomes was not so obvious. Many biologists were skeptical about Mendel’s laws of segregation and independent assortment until evidence mounted that they had a physical basis in the behavior of chromosomes. Concept 15.1 Mendelian inheritance has its physical basis in the behavior of chromosomes. Around 1900, cytologists and geneticists began to