康肾颗粒治疗慢性肾功能衰竭疗效探讨.docVIP

康肾颗粒治疗慢性肾功能衰竭疗效探讨 　　摘要：目的：探讨康肾颗粒治疗慢性肾功能衰竭的临床疗效。方法：选取88例患有慢性肾功能衰竭的患者并随机均分为一般治疗组、对照组以及治疗组。一般治疗组采用常规肾衰治疗如降压、纠正酸中毒、纠正贫血等，对照组患者在常规治疗的基础上加用口服尿毒清颗粒进行治疗，治疗组在常规治疗基础上加用口服康肾颗粒进行治疗。对三组患者治疗3个月前后的临床指标变化与临床疗效进行对照比较。结果：三组患者进行治疗3个月后，内生肌酐清除率与血清肌酐水平方面，治疗组与对照组相比无统计学意义（P0.05），此两组患者与一般治疗组相比，差异具有统计学意义（P0.05）；临床疗效方面，治疗组优于对照组，两组患者均优于一般治疗组，三组比较差异具有统计学意义（P0.05）。结论：加用康肾颗粒对慢性肾功能衰竭进行治疗后，临床疗效显著，能够有效降低血清肌酐，提高内生肌酐清除率，患者无需增加排便次数，副作用较少，值得临床应用及推广。 　　关键词：康肾颗粒；血清肌酐；内生肌酐清除率 　　Discussion of kangshenkeli efficacy in the treatment of chronic renal failure 　　LinLin ZhuWeiPing ZhengJing 　　renal Department of internal medicine The Fifth Hospital Affiliated to Zhongshan University Zip code：519000 　　[Abstract] Objective： To investigate the clinical efficacy of Shenkang granule in the treatment of chronic renal failure. Methods： 88 patients with chronic renal failure were randomly divided into treatment group and control group in general， and the treatment group. The general treatment group with conventional treatment such as blood pressure， renal failure to correct acidosis， correct anemia， patients in control group were treated with oral administration of Niaoduqing particles on the basis of conventional therapy， the treatment group on the basis of conventional therapy， were treated with oral Kang Shen granules. On three groups of patients before and after 3 months of clinical index changes and the clinical effects were compared between. Results： the three groups of patients after 3 months of treatment， endogenous creatinine clearance rate and serum creatinine level， no significant difference in treatment group and the control group （P 0.05）， the two groups of patients compared with the normal group， the difference was statistically significant （P 0.05）； clinical curative effect， treatment group than the control group， two patients in treatment group were superior to the general， the difference between the three groups was significant （to have statistical significance （P 0.05））. Conclusion： combined wit