Chapter5Tcells题材.ppt

NKT细胞是联系固有免疫和获得性免疫的桥梁 固有免疫 DC NKT NK IL-2 获得性免疫 活化 IFN-γ IFN-γ * * 5. CD 40L(CD154): Expressed on activated T cell Bind to CD40molecules on antigen-presenting cells Signal both to APCs and T cells to be more activated Indispensable for activation and class-switching of B cells 6. Mitogen receptor A. Classification on TCR TCRαβT cell TCR has enormous diversity. Antigen-recognition is MHC-restricted Distributed in secondary lymphoid tissue TCRγδT cell Diversity of TCR is limited，Antigen-recognition is not MHC-restricted Cytotoxicity, immune regulation, keep integrity of mucosa II. Subse