ThePrognosticValueofCirculatingTumorCellsinPatients.pptVIP

ThePrognosticValueofCirculatingTumorCellsinPatients.ppt

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ThePrognosticValueofCirculatingTumorCellsinPatients.ppt

The Prognostic Value of Circulating Tumor Cells in Patients with Melanoma: A Systematic Review and Meta-analysis by Simone Mocellin, Dave Hoon, Alessandro Ambrosi, Donato Nitti, and Carlo Riccardo Rossi Clin Cancer Research Volume 12 15 :4605-4613 August 1, 2006 ?2006 by American Association for Cancer Research Methodologic flow chart of the systematic review. Simone Mocellin et al. Clin Cancer Res 2006;12:4605-4613 ?2006 by American Association for Cancer Research Quality of studies included in the systematic review. Simone Mocellin et al. Clin Cancer Res 2006;12:4605-4613 ?2006 by American Association for Cancer Research CTC positivity rates observed in 3,667 patients with TNM stage I to IV melanoma compared with the 5-year mortality rates. Simone Mocellin et al. Clin Cancer Res 2006;12:4605-4613 ?2006 by American Association for Cancer Research Forest plot of HRs for overall survival from 13 studies 1,078 patients . Simone Mocellin et al. Clin Cancer Res 2006;12:4605-4613 ?2006 by American Association for Cancer Research Forest plot of HRs for PFS from 15 studies 1,871 patients . Simone Mocellin et al. Clin Cancer Res 2006;12:4605-4613 ?2006 by American Association for Cancer Research Methodologic flow chart of the systematic review. Quality of studies included in the systematic review. Gray areas of columns, percentage of studies reporting each single variable or enrolling a number of patients greater than or equal to the sample size calculated according to the assumptions described in the text. White areas of columns, number of studies not reporting the data or not reaching the expected sample size. CTC positivity rates observed in 3,667 patients with TNM stage I to IV melanoma compared with the 5-year mortality rates. Forest plot of HRs for overall survival from 13 studies 1,078 patients . M, multivariate analysis Cox proportional hazard model ; U, univariate analysis log-rank test . Quality of studies included in the systematic review. Gray areas of c

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