抗生素的使用幻灯片.pptVIP

* The administration of meropenem via continuous infusion is associated with a high rate of clinical cure in patients infected with P aeruginosa and other pathogens A retrospective cohort study by Lorente and colleagues compared continuous versus intermittent infusions of meropenem in 89 patients with VAP due to Gram-negative bacilli 42 patients received meropenem by continuous infusion (1 g over 6 hours q6h) 47 patients received meropenem by intermittent infusion (1 g over 30 minutes q6h) The rate of clinical cure was higher with the continuous infusion than with the intermittent infusion A