药物传输技术.pptVIP

Polymeric Drug Delivery Polymeric Drug Delivery Controlled Release vs. Sustained Release Sustained release Complexation, slowly dissolving coatings, use of derivatives with reduced solubility Sensitive to environmental conditions to which they are exposed Controlled release Release rate is determined by the device itself More accurate, predictable administration rate Polymeric Drug Delivery Systems Incorporate drug into a polymeric matrix Release drug at a known rate over a prolonged duration Release drug directly to the site of action Constant release - often the goal - difficult to achieve D