Clinical cytogenetics.pptVIP

Clinical cytogenetics Disorders of the autosomes and the sex chromosomes Outline First discuss the most common autosomal disorders; Second discuss the unique biology of X and Y chromosomes and sex chromosome abnormalities. Third discuss disorders of gonadal development and sexual differentiation; Autosomal disorders Trisomy 21 (Down syndrome) Trisomy 18 (Edwards Syndrome) Trisomy 13 (Patau Syndrome) Common phenotype Growth retardation Mental retardation Multiple congenital anomalies Down syndrome Or trisomy 21,is the most common chromosome disorders and is the most common genetic cause of m