The hypothesis of the interaction between pMHC and TCR.docVIP

The hypothesis of the interaction between pMHC and TCR Author name: Xia Shuqi Address: Room 505, North ladder, Tiansheng Building, No.35, Tiyu East Road, Tianhe District, Guangzhou, China Code: 510620 Tel: 020 Fax: 020 E-mail: xiashuqi@163.com The interaction between MHC, epitope peptide and TCR in the T cell specific immune response is very complicated, which is caused by the wide diversity of TCR and pMHC (peptide-MHC ).In this paper, an inference in the form of assumptions and summarize, analyzes the interaction between them, which makes it more regular and easier to understand. One, the formulation assumed and summarized in the interaction between pMHC and TCR The beginning or the end of the reaction between a pMHC and a TCR, is decided by their quantities and the selection affinity between them. Therefore, the concentration (or frequency) and the selection affinity[1] of the two sides should have the following relationship: F1×F2×Q＝T (F1 is the concentration or frequency of a pMHC，and F2 is the concentration or frequency of a TCR. F1 and F2 mainly decide the chance, and have the relationship to the occurrence probability of the reaction；Q is the selection affinity between the F1 and F2, whose value may be affected by temperature. Q ，which is affected by the structure of F1 and F2, mainly decide the inevitability.朗读显示对应的拉丁字符的拼音 ? 字典 名词 序言 前言 序 自序 绪言 绪论 动词 作序 写前言 可翻译 50 多种语言 ?????? Buongiorno Principessa! Wie hei?en Sie? děti Es ist sehr interessant! ???? nazdar! ?? ??? ??? ????? hoje está ensolarado Простите rouge miracoloso ????? V?r s? snill Hjelp! haydi gidelim hello ??????? Je ne sais pas ! Wie gehts? Wie bitte? ?? ???? ??????? ???. παραλ?α s? t? mijn vriend escargots La voiture さようなら χρησμ?? Ich bin vierzig Jahre alt 緾髆o est醩?on Je parle un petit peu fran鏰is. Pardon ?? ??? ?? ???! T is the co-existence constant).Transform the equation, and then there generates F1＝（T/F2）×（1/Q）. If the frequency of F2 in a individua