chapter 22 Immune response to infectious diseases.pptVIP

Immune response to parasites The diversity of parasitic universe makes it difficult to generalize Protozoan Th1-mediated effects, CTL IgG, IgM antibody Helminths IgE mediates activation of eosinophils, mast cells and basophils. Most immunities against parasites are non-sterilizing Premunition and concomitant immunity Balb/C BL/6 Th 1 response Death Th 2 response IL-12 αIL-12/αIFN-γ Recovery Th1 and Th2 response determine the outcome of immune response in the mice model of Leishmania Major infection Mechanisms of pathogens to evade host defense Constantly changing of antigens Inhibition o