Ch-2-Pharmacoki-.ppt

Pharmacokinetics-2 Lin Yuan Ph.D Prof Pharmacokinetics Q-1 Describe what is pharmacokinetics? Studying of the dynamic changes of drugs in the body, that is, the process of absorption, distribution, biotransformation (metabolism) and excretion of drugs in the body. Research application : Quantitative description of the time course of drug and metabolite concentrations in plasma, tissue and urine. Therapeutic Applications: Guide for drug choice and adjustment of dosage Drug trans-membrane transport I. The way of transport To achieve therapeutic effects, drugs need to cross