精子激活相关机制的研究进展.docVIP

精子激活过程中基础和临床研究 姚兵 摘要 早在六十多年前人们就开始研究配子的激活。在睾丸中，精子处于减数分裂和代谢休眠状态，需要经历一系列的信号交流才能使其功能发生转变，最终完成受精。但其激活过程较为复杂，相关的机制处于不断发现和认识阶段。本文就精子诱导激活过程及相关机制的最新进展作一综述。 关键词 精子；配子激活；受精 Basic and clinical studies on sperm activation Abstract Gamete activation has been studied for decades. In the testis, spermatozoa are in a state of meiotic and metabolic quiescence, and a series of reciprocal signals being activated are required for fertilization. The detail procedure and mechanism are found and understood continuously in recent years. This review summarizes the latest developments of sperm activation and