中枢兴奋药CentralStimulants.pptVIP

中枢兴奋药 Central Stimulants Central Stimulants Definition: Drugs that can stimulate the central nervous system. Classification: Cerebral cortex stimulation: Caffeine, Theophylline?… Cerebrum and brain stem stimulation: Nikethamide, Dimefline and Lobeline. Spinal cord stimulation: Strychnine Caffeine(咖啡因) 【Mechanism of Action】 Inhibit phosphodiesterase, decrease the degradation of cAMP→cAMP↑…… →physiological effect Central neuromodulator antagonist → effect of adenosine →block the inhibiting effect of adenosine on central nervous system→stimulate the central nervous system. Increasing int