关于氨基酸和神经肽与疼痛关系的研究(医学课件).pptVIP

Background 背景 Cerebral spinal fluid (CSF) reflects metabolic state of brain 脑脊液反映疼痛的新陈代谢状态 Analysis of CSF amino acids and peptides – highly relevant in pain perception and also neurological diseases 脑脊液中氨基酸和缩氨酸与疼痛感知和神经系统疾病高度相关 Chronic Pain – inflammatory, neuropathy and cancer 慢性疼痛分类—发炎，神经系病，癌症 Mechanisms very challenging and not yet understood 对于疼痛机制，目前还没有被足够的了解，非常具有挑战性 Lack of effective therapeutics 缺乏有效的治疗法 Background Excitatory and inhibitory amino acids and also nitric oxide (NO) are involved in pain modulation. 兴奋性，抑制性氨基酸和一氧化氮涉及到对疼痛的调节 Neuropeptides are i