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Impact of Hunt-Hess grade on the glycemic status of aneurysmal subarachnoid hemorrhage patients Sayantani Ghosh1, Saugat Dey1, Mitchell Maltenfort2, Mathew Vibbert3, Jaqueline Urtecho3, Fred Rincon3, Jack Jallo11 Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA, USA, USA2 Department of Biostatistics, The Rothman Institute, Philadelphia, PA, USA, USA3 Department of Neurosurgery and Neurology, Thomas Jefferson University, Philadelphia, PA, USA Date of Submission 28-Feb-2012 Date of Decision 14-Apr-2012 Date of Acceptance 18-May-2012 Date of Web Publication 14-Jul-2012 Correspondence Address:Sayantani Ghosh136, Dr. Meghnad Saha Road, Pratyasha Apartments, Flat-4C, Kolkata 700074, India USA DOI: 10.4103/0028-3886.98510 ? Abstract Objective: This study has explored the impact of Hunt-Hess (H-H) grade of aneurysmal subarachnoid hemorrhage (aSAH) on the glycemic status of such patients during their intensive care unit (ICU) stay and has also analyzed whether H-H grade predicts their outcome independent of their glycemic status. Materials and Methods: This was a retrospective case record review of prospectively maintained database of 1090 previously non-diabetic aSAH patients admitted to Thomas Jefferson University Hospital, Philadelphia. H-H grade of SAH, serum and CSF glucose on admission, serum glucose on the day of surgery and 14 days post-surgery, as well as the extended Glasgow Outcome Score (GOS-E score) at discharge were noted. After univariate analysis, significant variables (P 0.05) were entered into a logistic regression model to identify significant associations with admission H-H grade. Results: Although admission serum glucose was significantly higher for H-H grades 4-5 than grades 1-3 (P 0.001); after postoperative day 4, the difference between the H-H grades got blurred. Admission CSF glucose was also significantly higher for H-H grades 3-4 than for grades 1-3 and 5 (P 0.001). H-H grades 4-5 were related wit