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1664年,微生物学的先驱列文虎克曾用原始的显微镜对生长在皮革表面及蔷薇枯叶上的霉菌进行观察。1676年,首次观察到了细菌。 Pasteur trained as a chemist, and made a lasting contribution to the science of stereochemistry before turning his attention to spoilage problems in the wine industry. He noticed that when lactic acid was produced in wine instead of alcohol, rod-shaped bacteria were always present, as well as the expected yeast cells. This led him to believe that while the yeast produced the alcohol, the bacteria were responsible for the spoilage, and that both types of organism had originated in the environment. In respo
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