酒精与营养.pptVIP

* * For one, the accumulation of hydrogen ions during alcohol metabolism shifts the body’s acid –base balance toward acid. For another, the accumulation of NADH slows the TCA cycle, so pyruvate and acetyl CoA build up. Excess acetyl CoA then takes the route to fatty acid synthesis, and fat clogs the liver. * * Fat accumulate can be seen in the livers of young men after a single night of heavy drinking. The first stage of liver deterioration seen in heavy drinkers is therefore known as fatty liver; it interferes with the distribution of nutrients and oxygen to the liver cells. If the condition