2014乳腺癌内分泌治疗年度进展.pptVIP

小结 预防： IBIS-1 辅助： TEXTSOFT 、 POEMS 、ABCS8 新辅助：OPPORTUNE研究 晚期：FERGI、PALOMA-1、 FIRST、China CONFIRM 个体化内分泌预防与治疗 内分泌联合靶向 谢谢！ * The primary endpoint was frequency of breast cancer (including DCIS). Predefined subgroups were oestrogen receptor status of the cancer, use of hormonal replacement therapy, and age (50, 50 years) Secondary endpoints were other cancers, thromboembolic events, cardiovascular events, and cause-specific mortality. * Methods: 7154 pre- and postmenopausal women were randomised to receive daily 20mg tamoxifen (N=3579) or matching placebo (N=3575) for