pUDKH基因治疗犬下肢缺血后对血管、肌肉组织的影响.docVIP

pUDKH基因治疗犬下肢缺血后对血管、肌肉组织的影响 作者：哈小琴，赵治华，吕同德，李元敏，任建平，吴祖泽 【关键词】 pUDKH基因；血管；肌肉；组织病理 【Abstract】 AIM: To observe the effects of pUDKH administration locally on blood vessels and muscles in dogs with hindlimb ischemia. METHODS: Dogs were anesthetized with an intravenous injection of sodium pentobarbital . Then the left external iliac artery as well as all of the above arteries were ligated completely with silk thread. Thus the completely ischemic hindlimb model was established. The dogs with completely ischemic hindlimb were randomly pide