缬沙坦与硝苯地平缓释片治疗原发性高血压临床疗效观察.docVIP

缬沙坦与硝苯地平缓释片治疗原发性高血压临床疗效观察 　　【摘要】 目的：观察原发性高血压患者采用缬沙坦与硝苯地平缓释片治疗的临床效果。方法：选取2009年12月-2012年12月笔者所在医院收治的原发性高血压患者220例，随机将所有患者平均分成A1组（110例）与A2组（110例）。A1组患者采用缬沙坦+硝苯地平缓释片治疗，A2组患者选择缬沙坦治疗。均治疗28 d，对比A1组患者与A2组患者完成治疗后的降压效果以及不良反应情况。结果：A1组与A2组患者完成治疗后，降压效果均比较明显，A1组患者中，共有2例患者降压无效，总有效率达98.18%；A2组患者中，16例患者降压无效，总有效率为85.45%，两组总有效率比较差异有统计学意义（P0.05）。A1组收缩压以及舒张压与治疗前比较，差异有统计学意义（P0.05）。两组均未出现严重不良反应。结论：针对原发性高血压患者，采用缬沙坦+硝苯地平缓释片治疗，患者临床疗效确切，成功凸显临床应用意义。 　　【关键词】 缬沙坦； 硝苯地平缓释片； 原发性高血压 　　中图分类号 R544.1 文献标识码 B 文章编号 1674-6805（2014）12-0024-02 　　The Clinical Curative Effect Observation of Valsartan and Nifedipine Sustained Release Tablets in the Treatment of Primary Hypertension/ZHANG Nian-yu.//Chinese and Foreign Medical Research，2014，12（12）：24-25 　　【Abstract】 Objective：To observe the clinical effect of Valsartan and Nifedipine Sustained Release Tablets in the treatment of primary hypertension.Method：220 cases with essential hypertension in our hospital from December 2009 to December 2012 were randomly divided into A1 group（110 cases） and A2 group（110 cases）.The A1 group was treated with Valsartan and Nifedipine Sustained Release Tablets，the A2 group was treated with Valsartan.28 d treatment for all patients，the hypotensive effect and adverse reaction were compared in A1 group and A2 group patients after the treatment.Result：The effect of antihypertensive in two groups were more obvious，2 cases blood pressure was no effect，the total effective rate was 98.18% in the A1 group；16 cases blood pressure was no effect，the total effective rate was 85.45% in A2 group，the total efficiency in two groups was significant difference（P0.05）.Systolic blood pressure and diastolic blood pressure in A1 group after completing treatment compared with before treatment were significant differences（P0.05）.There were no serious adverse reaction in two groups.Conclusion：For patients with essential hypertension Valsartan and Nifedipine Sustained Release Tablets in the treatment of patients，the clinical curative effect is ex