奥美拉唑治疗急性非静脉曲张性上消化道出血的效果观察.docVIP

奥美拉唑治疗急性非静脉曲张性上消化道出血的效果观察 　　[摘要] 目的 探讨奥美拉唑治疗急性非静脉曲张性上消化道出血的疗效性和安全性。 方法 选择2010年1月～2012年12月本院收治的98例急性非静脉曲张性上消化道出血患者作为观察对象，根据不同用药方法分为观察组（47例）和对照组（51例），对照组给予常规治疗，观察组在对照组基础上给予奥美拉唑静脉滴注，观察两组的疗效性和安全性。 结果 观察组总有效率达95.7%，对照组总有效率为72.5%，两组差异有统计学意义（P0.05）；观察组止血时间较对照组明显缩短，差异具有统计学意义（P0.05）；两组在治疗过程中未见明显不良反应。结论 奥美拉唑结合常规方法治疗急性非静脉曲张性上消化道出血临床疗效显著，止血时间较短，安全性较高，值得临床推广应用。 　　[关键词] 非静脉曲张性上消化道出血；奥美拉唑；止血敏；疗效观察 　　[中图分类号] R573.2 [文献标识码] A [文章编号] 1674-4721（2013）11（b）-0080-02 　　Observation on the effect of omeprazole in the treatment of acute non variceal upper gastrointestinal hemorrhage 　　LAI Shen-wei ZHANG Xu ZHU SHU-sheng 　　Department of Internal Medicine of Digestive Tumor， People′s Hospital of Yudu County in Jiangxi Province， Yudu 342300，China 　　[Abstract] Objective To investigate the efficacy and safety of omeprazole in the treatment of patients with acute non variceal upper digestive tract hemorrhage. Methods 98 cases of patients with acute non variceal upper gastrointestinal bleeding from January 2010 to December 2012 in our hospital were selected as research objects， according to the different drugs， the cases were divided into observation group （47 cases） and control group（51 cases）， control group was given conventional treatment， observation group was given omeprazole note based on control group， the effect and safety of the two groups were observed. Results In observation group， the total effective rate was 95.7%， that of control group was 72.5%，the difference between two groups was significant （P0.05）；bleeding stop time of observation group was significantly shorter than control group， the difference was statistically significant（P0.05）； no obvious adverse reaction in two groups was found in the course of treatment. Conclusion The effect of omeprazole in the treatment of acute non variceal upper gastrointestinal hemorrhage is exact， hemostatic time is short， security is high， is worthy of clinical application. 　　[Key words] Non variceal upper gastrointestinal bleeding； Om