甲泼尼龙琥珀酸钠辅助治疗小儿重症肺炎的临床疗效研究.docVIP

甲泼尼龙琥珀酸钠辅助治疗小儿重症肺炎的临床疗效研究 　　摘 要：目的：探究甲泼尼龙琥珀酸钠辅助治疗小儿重症肺炎的临床治疗效果。方法： 选取我院2012年6月～2014年6月儿科住院部50例重症肺炎患儿作为研究对象，随机分为对照组和治疗组组，对照组患儿予以常规抗感染及呼吸支持等对症支持治疗，治疗组在对照组患儿治疗的基础上辅助使用甲泼尼龙琥珀酸钠治疗，观察两组患儿临床疗效及临床症状改善时间、住院时间。结果： 两组患儿治疗后临床总有效率比较，治疗组明显高于对照组，p0.05，差异具有统计学意义；两组患儿治疗后临床症状改善时间、重症监护时间比较，治疗组明显比对照组短，p0.01，差异具有统计学意义。结论：采用甲泼尼龙琥珀酸钠辅助治疗小儿重症肺炎具有显著的临床治疗效果，可明显改善患儿临床症状，缩短患儿重症监护时间，值得临床应用以及推广。 　　关键词：甲泼尼龙琥珀酸钠；小儿重症肺炎；疗效 　　Abstract：Objective Clinical therapeutic effect of methylprednisolone sodium succinate in adjuvant treatment of Infantile Severe pneumonia. Method Methods in our hospital in 2012 June ～2014 year in June 50 cases of pediatric inpatient children with severe pneumonia as the research object， randomly divided into control group and treatment group， control group were treated with conventional anti infection and respiratory support， symptomatic treatment， the treatment group in the control group were treated on supporting the use of methylprednisolone sodium succinate treatment， clinical observation two groups of children with symptoms and clinical improvement time， hospitalization time. Result The two groups after treatment the total clinical efficiency comparison， the treatment group was significantly higher than that in the control group， P 0.05， the difference was statistically significant； treatment of two groups of children with clinical symptoms， compared with the time duration of intensive care， treatment group was shorter than the control group， P 0.01， the difference was statistically significant. Conclusion Use of methylprednisolone sodium succinate in adjuvant treatment of Infantile Severe Pneumonia with clinical treatment effect is significant， can significantly improve the clinical symptoms， shorten the duration of intensive care patients， is worthy of clinical application and promotion. 　　Key words：Methylprednisolone sodium succinate；Children with severe pneumonia；Curative effect 　　肺炎是儿科比较常见的一种疾病，重症肺炎死亡率极高，在发展中国家婴儿以及5岁以下的儿童因为肺炎致死者占儿童死亡的20.0%～40.0%[1]。其临床表现为频