刘小龙-循环肿瘤DNA(ctDNA)检测策略及临床意义要素.ppt

* * We used digital polymerase chain reaction – based technologies to evaluate the ability of circulating tumor DNA (ctDNA) to detect tumors in 640 patients with various cancer types. * * * * * * * Percentage of bins showing hypomethylation in HCC patients and chronic hepatitis B virus (HBV) carriers with cirrhosis (A). ROC curves for HCC patient detection using hypomethylation (B) and CNA (C) analyses. The P values shown are for the comparisons between using all sequenced reads from one lane and using 10 million reads. Our cohort of 388 patients with primary breast cancer before chemotherap